3d打印片剂填充形状对药物溶出度的影响

Medical Sciences Forum Pub Date : 2021-07-20 DOI:10.3390/msf2021005015

Nuno Venâncio, Gabriela G Pereira, João Pinto, Ana Fernandes

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引用次数: 4

摘要

以患者为中心的治疗在儿科尤为重要，可以通过三维打印来实现。通过热熔挤压生产含有30% w/w茶碱的细丝，并使用熔融沉积建模印刷以生产片剂。本文报道了填充形状(十字、星形、栅格)对药物含量和释放影响的初步结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Influence of the Infill Geometry of 3D-Printed Tablets on Drug Dissolution

Patient-centric therapy is especially important in pediatrics and may be attained by three-dimensional printing. Filaments containing 30% w/w of theophylline were produced by hot-melt extrusion and printed using fused deposition modelling to produce tablets. Here, preliminary results evaluating the effect of infill geometry (cross, star, grid) on drug content and release are reported.

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Medical Sciences Forum

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