卢旺达Kibuye转诊医院与2型糖尿病相关的危险因素——一项病例对照研究

Egide Freddy Muragijimana
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摘要

背景2型糖尿病(T2DM)在全球范围内呈上升趋势,是导致过早死亡的主要原因之一。如果不采取大胆行动,到2025年,十分之九的糖尿病患者将患有2型糖尿病。目的:本研究旨在评估Kibuye转诊医院T2DM患者的社会人口学特征,并确定与T2DM相关的生活方式因素。方法采用基于医院的病例对照研究设计。使用了改编自世卫组织的食物频率和全球身体活动问卷。所有研究分析均使用SPSS v 23。使用描述性统计,借助频率和百分比对分类变量进行汇总。采用二元logistic回归,通过计算比值比和相应的95%置信区间来确定与T2DM相关的因素。通过控制混杂变量,建立T2DM独立危险因素的Logistic回归模型,显著性水平为5%。结果吸烟、体力活动水平、低水平饮食多样性与2型糖尿病相关。吸烟者患2型糖尿病的可能性约为吸烟者的9倍[AOR= 8.9;95%可信区间= 2.84 - -27.86;P <0.001]与不吸烟者相比。运动量低的被调查者患2型糖尿病的可能性是运动量高或中度的被调查者的8.1倍[AOR= 8.1;95%可信区间= 2.90 - -22.79;p < 0.001)。同样,饮食多样性得分低的受访者患t2dm的可能性是其6倍[AOR= 6.03;95%可信区间= 1.67 - -21.80;P =0.006]与饮食多样性评分高的人群相比。结论与2型糖尿病密切相关的生活方式因素均可通过促进体育锻炼、健康生活方式和饮食多样性等公共卫生干预措施加以改变。卢旺达医学与健康科学杂志2022;5(2):151-157
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk factors associated with Type 2 Diabetes Mellitus at Kibuye Referral Hospital, Rwanda- A case control study
BackgroundType 2 Diabetes Mellitus (T2DM) is increasing globally, being among the leading cause of premature mortality. If no bold actions are taken, nine in ten persons diagnosed with diabetes will have T2DM by 2025.ObjectivesThis study aims at assessing socio-demographic characteristics and identify lifestyle factors associated with T2DM at Kibuye Referral Hospital.MethodsHospital-based case control study design was used. Food frequency, and global physical activity questionnaires adapted from WHO were used. SPSS v 23 was used for all research analysis. Descriptive statistics were used to summarize categorical variables with help of frequencies and percentages. Binary logistic regression was used to identify the factors associated with T2DM by computing odds ratio with corresponding 95% confidence interval. Logistic regression models using multivariate analysis with a significance level of 5% was used to establish the independent risk factors of T2DM by controlling the confounding variables.ResultsSmoking, level of physical activity, low level of dietary diversity were associated with T2DM. The likelihood of developing T2DM among smokers was about 9 times more [AOR= 8.9; 95%CI=2.84-27.86; p<0.001] compared to non- smokers. Respondents with low level of physical activities were 8.1 times more likely to get T2DM than those with high or moderate physical activities [AOR= 8.1; 95%CI= 2.90-22.79; p<0.001]. Similarly, respondents with low level of dietary diversity score were 6 times more likely to developT2DM [AOR= 6.03; 95%CI= 1.67-21.80; p=0.006] compared to those with high level of dietary diversity score.ConclusionLifestyle factors that showed strong association with T2DM can all be modified by public health interventions that are promoting physical activity, healthy lifestyle, and dietary diversity. Rwanda J Med Health Sci 2022;5(2):151-157
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