内啡肽激素对妊娠焦虑的预测作用

P. Senudin, S. Syamsuddin, A. A. Nurdin
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引用次数: 2

摘要

妊娠焦虑是一种常见的问题,患病率为14-54%,在妊娠晚期最高。妊娠焦虑通过促肾上腺皮质激素释放激素(CRH)、促肾上腺皮质激素(ACTH)和皮质醇的合成和释放增加,抑制内啡肽激素的产生,与下丘脑垂体肾上腺(HPA)轴通路的神经递质失调和内分泌改变有关。本研究旨在确定内啡肽水平与妊娠焦虑的关系。本研究是一项观察性研究,采用横断面方法对57名孕妇进行研究。采用汉密尔顿焦虑评定量表(HARS)测定焦虑水平,血浆标本ELISA检测内啡肽水平。结果显示,内啡肽水平是妊娠焦虑的预测因子(p = 0000)。关键词:焦虑,妊娠,内啡肽
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE ROLE OF ENDORPHIN HORMONES AS PREDICTORS OF PREGNANCY ANXIETY
Pregnancy anxiety is a common problem with a prevalence of 14-54% and is the highest in the third trimester. Pregnancy anxiety is associated with neurotransmitter dysregulation and endocrine changes in the Hypothalamus Pituitary Adrenal (HPA) axis pathway through the increase of synthesis and the release of corticotropin-releasing hormone (CRH), Adrenocorticotropic Hormone (ACTH) and cortisol to suppress endorphin hormone production. This study aims to determine the relationship of endorphin hormone levels to pregnancy anxiety. This study was an observational study using a cross-sectional approach to 57 pregnant women. The anxiety level was measured by using the Hamilton Anxiety Rating Scale (HARS) and the ELISA kit with plasma specimens was employed to examine the endorphin hormone levels. The results showed that endorphin hormone levels acted as predictors of pregnancy anxiety (p = 0,000). Keywords: Anxiety, Pregnancy, Endorphin  
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