数字乳房x线照片对乳腺癌检测的分析

H. A. Nugroho, N. Faisal, I. Soesanti, L. Choridah
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引用次数: 10

摘要

数字乳房x光检查已成为早期乳腺癌检测最有效的技术。肿块是乳腺癌最常见的异常。挑战在于早期和准确的发现,以克服影响全世界越来越多妇女的乳腺癌的发展。计算机辅助诊断(CAD)用于帮助放射科医生解释和识别乳房x光片异常的模式。本研究的主要目的是执行和分析对比度增强和特征选择方法,以建立一个区分正常,良性和恶性的CAD。预处理需要改善图像的不良质量,去除预处理步骤产生的伪影。将感兴趣区域作为可疑区域进行分割,然后采用纹理特征的方法进行提取。通过特征选择技术选择高维的特征,并将其按彼此的类别进行分类。数字乳房x光照片取自日惹小坂肿瘤诊所的私人数据库。该数据集包括40张乳房x线照片,其中良性14例,恶性6例,正常20例。该方法在预处理步骤中通过MSE和PSNR值对图像进行增强和验证。采用直方图和灰度共生矩阵(GLCM)作为纹理特征提取可疑区域。使用基于相关性的特征选择(CFS)从之前提取的12个特征中选择最优特征。均值、标准差、平滑度、角秒矩(ASM)、熵和相关性是在特征维数较少的情况下保证分类精度提高的最佳特征。结果表明,该方法准确率为96.66%,灵敏度为96.73%,特异度为97.35%,ROC为96.6%,有望为放射科医师决策提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of digital mammograms for detection of breast cancer
Digital mammogram has become the most effective technique for early breast cancer detection. The most common abnormality that may indicate breast cancer is masses. The challenge lies in early and accurate detection to overcome the development of breast cancer that affects more and more women throughout the world. Computer Aided Diagnosis (CAD) is used to help the radiologist in interpretation and recognition the pattern of the mammogram abnormality. The main objective of this research is to perform and analyze the contrast enhancement and feature selection method in order to build a CAD to discriminate normal, benign, and malignant. Preprocessing needs to enhance the poor quality of image and remove the artifact caused by preprocessing step. ROI as the suspicious area segmented, and then extracted by texture feature approach. High dimensionality of feature is selected by feature selection technique and would be classified according to their class each other. The digital mammogram images are taken from the Private database of Oncology Clinic Kotabaru Yogyakarta. The dataset consists of 40 mammogram images with 14 benign cases, 6 malignant cases, and 20 normal cases. The proposed method in preprocessing step made the image enhanced and proved by MSE and PSNR value. Histogram and gray level co-occurrence matrix (GLCM) as the texture feature are used to extract the suspicious area. Correlation based feature selection (CFS) is used to select the best feature among 12 extracted features before. Mean, standard deviation, smoothness, angular second moment (ASM), entropy, and correlation are the best feature that guarantee the improvement of classification with less feature dimension. The result shows that the proposed method was achieved the accuracy 96.66%, sensitivity 96.73%, specificity 97.35% and ROC 96.6% It is expected to contribute for helping the radiologist as material consideration in decision-making.
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