甲磺丁胺治疗生长激素治疗的低能侏儒的血糖和血浆IRI水平。

E Soltysik-Wilk, M Rybak, W Golda
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引用次数: 0

摘要

在25例低生长营养性侏儒症(HSD)患儿中,通过使用甲苯丁胺刺激来评估胰岛的胰岛素生成功能。作者认为,低胰岛素释放和/或合成是这些儿童对HGH治疗的轻微生长反应的原因。这种低胰岛素反应与HSD儿童在HGH治疗后患糖尿病的倾向之间也可能存在因果关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Glycemia and plasma IRI level after tolbutamide in hyposomatrophic dwarfs treated with HGH.

The insulinogenic function of the pancreatic islets was assessed by the use of tolbutamide stimulation in 25 children with hyposomatotrophic dwarfism (HSD). The authors suggest that the low insulin release and/or synthesis is responsible for slight growth response of these children to HGH treatment. There may also be a causative relation between this low insulin response and the tendency of children with HSD to develop diabetes after HGH treatment.

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