M. Aditya, Rehmadanta Sitepu, Dion Notario, Fibe Y. Cesa
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引用次数: 0

摘要

高血压患者出现睡眠障碍或失眠可能与血管紧张素转换酶抑制剂(ACEI)、钙通道阻滞剂(CCB)等降压药物的副作用有关,但两组间的影响并没有太大的比较。因此,本研究采用病例对照设计,评估使用ACEI和CCB对失眠发生率的影响。通过data Collector Sheet和Athens insomnia Scale (AIS)问卷收集人口统计数据和失眠状况,然后进行单因素、双因素和多因素分析。结果显示,56 ~ 60岁年龄组接受ACEI治疗的患者失眠风险约为其他接受CCB治疗的患者的0.38倍(p=0.026, 95% CI=0.15 ~ 0.94),而在其他类别组中未发现显著相关性。因此,医疗保健专业人员对失眠副作用的监测变得非常重要,特别是对56-60岁接受CCB治疗的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pengukuran Risiko Gangguan Tidur pada Penggunaan Angiotensin Converting Enzyme Inhibitor dan Calcium Channel Blocker: Case Control Study di Puskesmas Dau, Malang
Sleep disorder or insomnia arisen in hypertensive patients might be derived as a side effect of antihypertensive mediations such as Angiotensin Converting Enzyme Inhibitor (ACEI) and Calcium Channel Blocker (CCB), but the influence of each group had not been much compared. Therefore, a research was conducted using case control design to assess the risk of using ACEI and CCB against the incidence rate of insomnia. Demographic data and insomnia status were collected through Data Collector Sheet and Athens Insomnia Scale (AIS) questionnaire before univariate, bivariate, and multivariate analysis was conducted. The result showed that in the age group of 56–60 years patients undergoing treatment with ACEI have a smaller risk of insomnia of approximately 0.38 times (p=0.026, 95% CI=0.15–0.94) compared to the other patients who were treated with CCB, while in other categorial groups, no significant relationship was found. Thus, the monitoring of insomnia side effects becomes important to be conducted by healthcare professional especially in patients undergoing treatment with CCB at the ages of 56–60 years.
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