肾DCE MRI检测急性肾排斥反应的影像分析

A. El-Baz, A. Farag, Rachid Fahmi, S. E. Yüksel, M. El-Ghar, T. Eldiasty
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引用次数: 31

摘要

急性排斥反应是肾移植后移植物衰竭最常见的原因,早期发现对移植肾功能的存活至关重要。本文介绍了一种动态磁共振成像(DCE-MRI)自动分类正常和急性排斥移植的新方法。该算法包括三个主要步骤;第一步是将肾脏与周围的解剖结构分离。在第二步中,采用一种新的非刚体配准算法来解释由于患者呼吸而引起的肾脏运动,最后,从皮质获得显示造影剂进入组织的灌注曲线,并用于正常和急性排斥移植的分类。该方法的应用产生了可喜的结果
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Image Analysis of Renal DCE MRI for the Detection of Acute Renal Rejection
Acute rejection is the most common reason of graft failure after kidney transplantation, and early detection is crucial to survive the transplanted kidney function. In this paper we introduce a new approach for the automatic classification of normal and acute rejection transplants from dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). The proposed algorithm consists of three main steps; the first step isolates the kidney from the surrounding anatomical structures. In the second step, a novel nonrigid-registration algorithm is employed to account for the motion of the kidney due to patient breathing, and finally, the perfusion curves that show the transportation of the contrast agent into the tissue are obtained from the cortex and used in the classification of normal and acute rejection transplants. Applications of the proposed approach yield promising results
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