在赞比亚四家主要医院进行的一项有关细针穿刺细胞学和组织病理学诊断腮腺肿瘤的横断面研究

S. Kazuma, L. Mucheleng'anga, R. Zulu, H. Hanna
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引用次数: 1

摘要

背景:针吸细胞学(FNAC)是一种廉价、简单、快速、微创的检查方法,广泛应用于腮腺肿瘤的术前诊断。方法:对赞比亚四家主要医院的25名患者进行为期两年的前瞻性研究。使用10cc注射器和20-22G针头进行FNAC采集,并用papanicolaou染色进行标本染色。采用血红素和伊红进行组织病理学评估,HE阳性预测值为95.7%,阴性预测值为100%,似然比为3。所有腮腺肿瘤均为肿瘤性,其中良性肿瘤占76%,恶性肿瘤占24%。FNAC准确诊断良性肿瘤68%,恶性肿瘤20%。结论:本研究发现FNAC与组织病理学诊断腮腺肿瘤有良好的相关性。FNAC在腮腺肿瘤的术前评估中是有用的,因为它提供了术前诊断,通过避免手术(炎性病变)和限制良性和恶性腮腺肿瘤的手术范围来影响治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A cross section study to correlate fine needle aspiration cytology and histopathology in the diagnosis of parotid tumoursat four major hospitals in Zambia
Background: Needle Aspiration Cytology (FNAC) is cheap, simple, quick, minimally invasive procedure that is widely used for preoperative diagnosis of Parotid tumours. Methods: Twenty five patients were prospectively studied over a two-year period at four major hospitals in Zambia. FNAC was done using a 10cc syringe and 20-22G needles for sample collection and specimen staining was done with papanicolaou stain. Histopathology was assessed with Haematoxylin and Eosin (HE positive and negative predictive values of 95.7% and 100% respectively and a likelihood ratio of 3. All Parotid tumours were neoplastic with 76% benign and 24% malignant tumours on histopathology. FNAC accurately diagnosed 68% benign and 20% malignant tumours. Conclusion: This study found that FNAC correlates well with histopathology in the diagnosis of parotid tumours. FNAC is useful in the preoperative assessment of Parotid tumours as it provides a preoperative diagnosis that influences management by either avoiding surgery (inflammatory lesion) and limiting the extent of surgery for benign and malignant Parotid tumours.
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