R. McLaughlin, L. Scolaro, B. R. Klyen, S. Hamza, P. Robbins, C. Saunders, D. Sampson
{"title":"正常的淋巴结结构可以用光学相干断层扫描来表征吗?","authors":"R. McLaughlin, L. Scolaro, B. R. Klyen, S. Hamza, P. Robbins, C. Saunders, D. Sampson","doi":"10.1117/12.815182","DOIUrl":null,"url":null,"abstract":"Assessment of lymph node involvement is a key prognostic marker in early breast cancer. This paper demonstrates the ability of optical coherence tomography (OCT) to characterise the micro-architecture of healthy, non-cancerous lymph nodes. OCT is shown to differentiate stroma, cortex and adipose tissue. Characteristic patterns are also identified for germinal centres and blood vessels within the node. Results are correlated against a histopathological gold standard.","PeriodicalId":184459,"journal":{"name":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","volume":"6 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2008-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Can normal lymph node architecture be characterised by optical coherence tomography?\",\"authors\":\"R. McLaughlin, L. Scolaro, B. R. Klyen, S. Hamza, P. Robbins, C. Saunders, D. Sampson\",\"doi\":\"10.1117/12.815182\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Assessment of lymph node involvement is a key prognostic marker in early breast cancer. This paper demonstrates the ability of optical coherence tomography (OCT) to characterise the micro-architecture of healthy, non-cancerous lymph nodes. OCT is shown to differentiate stroma, cortex and adipose tissue. Characteristic patterns are also identified for germinal centres and blood vessels within the node. Results are correlated against a histopathological gold standard.\",\"PeriodicalId\":184459,\"journal\":{\"name\":\"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics\",\"volume\":\"6 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1117/12.815182\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canterbury Workshop and School in Optical Coherence Tomography and Adaptive Optics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.815182","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Can normal lymph node architecture be characterised by optical coherence tomography?
Assessment of lymph node involvement is a key prognostic marker in early breast cancer. This paper demonstrates the ability of optical coherence tomography (OCT) to characterise the micro-architecture of healthy, non-cancerous lymph nodes. OCT is shown to differentiate stroma, cortex and adipose tissue. Characteristic patterns are also identified for germinal centres and blood vessels within the node. Results are correlated against a histopathological gold standard.