极低频脉冲电磁场对体外人淋巴细胞增殖及DNA修复的影响

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Pub Date : 1988-11-01 DOI:10.1109/IEMBS.1988.95245

F. Bersani, C. Franceschi, D. Monti, A. Bologni, C. Gatti, R. Cadossi, M. Nichelatti, G. Moschini, A. Cossarizza

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引用次数: 1

摘要

在两组健康受试者(平均年龄23岁和85岁)中研究了极低频电磁场对体外有丝分裂原诱导的淋巴细胞增殖的影响。在老年受试者中观察到细胞增殖的增加要多得多。这种影响取决于有丝分裂原的剂量和白细胞介素-2的产生和/或利用。对辐照后的DNA修复能力和细胞存活率也进行了评估，未发现遗传毒性效应。

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The effects of extremely low frequency pulsed electromagnetic fields (ELF) on human lymphocyte proliferation in vitro and DNA repair

The effect of extremely-low-frequency electromagnetic fields on in-vitro mitogen-induced lymphocyte proliferation was studied in two groups of healthy subjects (23 and 85 years, mean ages). An increase of cell proliferation was observed to be much higher in the group of aged subjects. The effects depended on the mitogen dose and involved interleukin-2 production and/or utilization. The DNA repair capability and cell survival in the exposed cultures after gamma irradiation was also evaluated, and no genotoxic effect was found.<>

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Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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