克森叶炖菜和黑洋葱提取物降低小鼠(小家鼠)血糖水平

Eni Sumarliyah, Dede Nasrullah, Sukadiono, Desta Pankyano
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引用次数: 0

摘要

糖尿病(DM)是一种以血糖升高为特征的代谢性疾病。糖尿病患者的血糖水平大多难以控制,这将威胁到并发症的发生。使用的替代疗法是降低血糖的活性类黄酮。本研究的目的是分析通过给小鼠喂食樱桃叶炖菜和黑洋葱对血糖水平的降低。本研究采用双侧实验设计(前测后测,对照组设计)。本研究的样本为32只小鼠,干预组16只,对照组16只。有自变量(克森叶炖菜和黑洋葱提取物)和因变量(血糖水平)。数据采用观察表收集,采用独立样本t检验和Kolmogorov Smirnov检验进行分析。本研究结果表明,樱桃叶煎液给药前后的差异为36.5 mg/dl,黑洋葱提取物给药前后的差异为24.3 mg/dl。虽然分析显示p = 0.98,但它表明两种提取物在降低小鼠血糖水平方面的有效性没有差异。得到了两种提取物对小鼠降血糖同样有效的比较试验结果。因此,需要更多的样本进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lowering blood sugar levels with kersen leaf stew (muntingia calabura l) and black onion (alium sativum) extract in mice (mus musculus)
Diabetes mellitus (DM) is a metabolic disease characterized by an increase in blood sugar levels. Blood sugar levels in patients with DM are mostly challenging to control, and this will threaten the occurrence of complications. Alternative therapies used are active flavonoids in reducing blood glucose. The purpose of this study was to analyze the decrease in blood sugar levels by administering cherry leaves stew and black onions to mice (mus musculus). The design of this study was the Quasy Experimental design (pretest-posttest with control group design). The sample in this study was 32 mice, 16 in the intervention group, and 16 comparison groups. There are independent variables (Kersen Leaf Stew and Black Onion Extract) and the dependent variable (Blood Glucose Level). The data were collected using an observation sheet, then analyzed using the independent sample T-test and Kolmogorov Smirnov test. The results of this study showed that the pre and post administration of cherry leaf decoction was 36.5 mg/dl, and the difference between pre and post administration of black onion extract was 24.3 mg/dl. While the analysis showed p = value 0.98, it showed no difference in the effectiveness of the two extracts in reducing blood sugar levels in mice. Obtained comparative test results from the two extracts were equally effective in lowering blood sugar in mice. Thus further research needs to be done with more samples.
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