An Overview of Machine Learning and HPC in Open Sources for Bioinformatics*

With development of recent open source software in HPC, such as Hadoop project, bioinformatics applications with large scale biological data can be solved more efficiently. The emerging machine learning algorithms are widely adapted for analysis, recognition and prediction. This paper will survey recent literatures about open source software of machine learning and HPC for bioinformatics applications. The commonly used machine learning algorithms for bioinformatics applications will be summarized here, and the situations of HPC adaption are also provided. Finally, the issues of future usages of machine learning for bioinformatics applications will be included.