老年2型糖尿病患者维生素D水平

F. Mahjoub, N. B. Amor, A. Guamoudi, C. Jemai, Ben Jemia Amani, Rihane Fatma, Olfa Beriche, Henda Jamoussi
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摘要

老年2型糖尿病患者的维生素D状况介绍:维生素D缺乏是一个全球性的健康问题。大约有10亿人缺乏维生素D。然而,其患病率在老年人中特别高。维生素D缺乏症的后果非常严重,如骨软化症、骨质疏松症伴骨质疏松性骨折风险、肌肉减少症、心血管事故增加、血压升高和血糖平衡改变。我们的研究旨在评估老年2型糖尿病患者维生素D的状况,并检测饮食中维生素D的缺乏。患者和方法:这项前瞻性观察性研究于2016年10月至2016年12月进行,涉及突尼斯国家营养研究所营养、糖尿病和代谢疾病A科住院的38例2型糖尿病患者。对所有患者进行了询问、全面体检、食物调查和生物样本调查。结果:研究人群的平均年龄为70.1±4.5岁。研究的大多数糖尿病受试者(95%)患有维生素D缺乏症,其中29%的病例证实缺乏维生素D。招募的受试者中没有一个人的膳食维生素D摄入量令人满意。维生素D缺乏症患者与推荐率的受试者之间有统计学差异的参数是:高血压、骨关节表现、空腹血糖和糖化血红蛋白。血清钙校正后p=0.02, r=+ 0.20。结论:虽然我们生活在一个全年阳光充足的国家,但突尼斯是维生素D缺乏患病率相当高的国家之一,尤其是在老年人中。因此,我们需要对老年人等高危人群采取预防措施和系统补充。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin D Status in ElderlyPatients with Type 2 Diabetes
Vitamin D Status in Elderly Patients with Type 2 Diabetes Introduction: Vitamin D deficiency is a problem with several health consequences worldwide. About 1 billion people are affected from Vitamin D deficiency. However, its prevalence is particularly high in the aged persons. The consequences of hypovitaminosis D are very serious such as osteomalacia, osteoporosis with risk of osteoporotic fractures, sarcopenia, increased cardiovascular accidents, increased blood pressure and alteration of the glycemic balance. Our study was conducted to evaluate the Vitamin D status and detect dietary deficiency on Vitamin D in elderly patients with type 2 diabetes. Patients and methods: This prospective observational study was performed between October 2016 and December 2016 involving 38 type 2 diabetic patients hospitalized in the department A of Nutrition, Diabetology and Metabolic Diseases at the National Institute of Nutrition in Tunis. An interrogation, a complete physical examination, a food survey and biological samples were done for all the patients. Results: The mean age of the study population was 70.1 ± 4.5 years. The majority of the diabetic subjects studied (95%) had hypovitaminosis D with a proven deficiency of the 29% of the cases. None of the subjects recruited had a satisfactory dietary intake of vitamin D. The parameters for which the difference was statistically significant between subjects with hypovitaminosis D and subjects with recommended rates were: high blood pressure, osteo-articular manisfestations, fasting blood glucose and HbA1c. Correlation was observed only with serum calcium corrected with p=0.02 and r=+ 0.20. Conclusion: Although we live in a very sunny country in the whole year, Tunisia is among the countries that have a fairly high prevalence of hypovitamin D, especially in elderly people. Hence we need preventive measures and systematic supplementation for groups at risk such as elderly.
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