Intraoperative antibiotics in the prevention of experimental dacron graft infection.

Moore and colleagues have shown that newly inserted Dacron-) vascular grafts are very susceptible to infection from circulating bacteria.’ Since S. Martin Lindenauer demonstrated in 1967 that prophylactic use of penicillin prevented the infection of Teflon patch grafts in a group of five dogs, experiments have been designed to justify the widespread use of prophylactic antibiotics in vascular surgery.’ 6