阵发性夜间血红蛋白尿,表现为溶血性贫血伴急性肾损伤

A. Bhawane, M. Balwani, A. Pasari, P. Tolani
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摘要

阵发性夜间血红蛋白尿(PNH)是一种获得性疾病,以低级别慢性溶血性贫血伴血小板减少或白细胞减少为特征,通常继发于慢性含铁血黄素小管沉积的良性肾脏累及。急性肾损伤(AKI)可以在溶血危象中看到。我们报告一例45岁男性PNH患者在带状疱疹感染后发展为可逆性AKI,需要临时血液透析支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paroxysmal nocturnal hemoglobinuria manifesting as hemolytic anemia with acute kidney injury
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by low-grade, chronic hemolytic anemia accompanied by either thrombocytopenia or leukopenia with usually benign kidney involvement secondary to chronic tubular deposition of hemosiderin. Acute kidney injury (AKI) may be seen during hemolytic crisis. We report the case of a 45-year-old man with PNH who developed reversible AKI requiring temporary hemodialysis support following herpes zoster infection.
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