急性心肌梗死后心肌肌钙蛋白释放的预测数学模型

2017 IEEE 14th International Conference on Networking, Sensing and Control (ICNSC) Pub Date : 2017-05-01 DOI:10.1109/ICNSC.2017.8000166

A. Procopio, Mariaconcetta Bilotta, A. Merola, F. Amato, C. Cosentino, S. Rosa, C. Covello, J. Sabatino, A. D. Luca, C. Indolfi

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引用次数: 4

摘要

目前的工作提出了一种新的模型在血液中释放心肌肌钙蛋白T (cTnT)，急性心肌梗死的生物标志物。从分子和细胞水平的基础机制出发，利用临床实验数据集，我们设计了一个能够捕捉cTnT释放曲线特征的数学模型。该模型旨在为临床医生提供一个有效的工具来评估心脏损伤的类型和程度，以及可用于改进诊断和治疗计划阶段的具体临床参数。

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Predictive mathematical model of cardiac troponin release following acute myocardial infarction

The present work proposes a novel model of the release in the blood of cardiac troponin T (cTnT), a biomarker of acute myocardial infarction. Starting from the underpinning mechanisms at the molecular and cellular level, and leveraging a clinical experimental dataset, we have devised a mathematical model that is able to capture the characteristic features of the release curve of cTnT. The model aims at providing the clinicians with an effective tool to evaluate the type and extent of cardiac damage and specific clinical parameters that can be used to improve the diagnosis and treatment planning phases.

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来源期刊

2017 IEEE 14th International Conference on Networking, Sensing and Control (ICNSC)

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