利用fret探针检测dna -配体静电相互作用

Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP) Pub Date : 1900-01-01 DOI:10.1364/3d.2022.jw5d.5

C. Murade, G. Shubeita

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引用次数: 0

摘要

DNA与配体的相互作用主要是静电作用，因为DNA在生理条件下是一个高电荷分子。在这里，我们提出了一种基于fret的传感器，它可以光学报告DNA和带电配体之间的这些相互作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Detecting DNA-Ligand Electrostatic Interactions With a FRET-Based Probe

DNA-ligand interactions are dominated by electrostatics as DNA is a highly charged molecule at physiological conditions. Here, we present a FRET-based sensor which can optically report on these interactions between DNA and charged ligands.

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Imaging and Applied Optics Congress 2022 (3D, AOA, COSI, ISA, pcAOP)

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