磁热疗中磁性纳米颗粒空间分布模式对温度分布的影响

2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med) Pub Date : 2018-09-01 DOI:10.23919/EMF-MED.2018.8526038

Gurmeet Singh, Neeraj Kumar, P. Avti

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引用次数: 2

摘要

分析了磁性纳米颗粒(MNP)诱导热疗过程中均匀注射和非均匀注射(单点注射和多点注射)方式下瘤内注射纳米颗粒的温度分布。采用有限体积法对Pennes生物热方程进行数值求解，求得温度分布。分析是在一个三维模型上进行的，该模型描绘了一个被健康组织包围的肿瘤。观察到，多位点MNP注射在肿瘤内提供了更好的整体温度分布。

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Effects of spatial distribution patterns of magnetic nanoparticles on temperature distribution in magnetic hyperthermia

Temperature profiles of intratumorally injected nanoparticles in uniform and nonuniform (single and multi-site injection) manner during magnetic nanoparticle (MNP) induced hyperthermia are analyzed. Finite volume method is used to numerically solve the Pennes’ bioheat equation, to evaluate the temperature distribution. The analysis is carried out on a three-dimensional model that depicts a tumor surrounded by healthy tissues. It is observed that multi-site MNP injection offers a better overall temperature distribution within the tumor.

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2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med)

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