S. Ramya, S. Praveen Kumar, T. K. Srinivasan, T. Aravind, G. Ram, D. Lingaraja
{"title":"基于MEMS的微流控通道血细胞分选芯片","authors":"S. Ramya, S. Praveen Kumar, T. K. Srinivasan, T. Aravind, G. Ram, D. Lingaraja","doi":"10.1109/ICOSEC54921.2022.9952048","DOIUrl":null,"url":null,"abstract":"Hydraulic jump concept is used to separate and capture blood cells in this study. The two-dimensional microfluidic simulation model is used to create the devices. In many medical tests, physical features of cells of interest, such as size, deformability, and electric and magnetic properties, have become more important because of the inherent difficulties of isolation techniques based on biomarkers and antigens. In this study, cell/particle sorting in microchannels is investigated by using the inherent hydrodynamic effects. Microfluidic hydraulic jumps may be induced by turning high-speed flow in a microfluidic channel into a flow that has high potential energy by varying the channel height, much as in macrofluidics. Cells of varying sizes have their own chambers, such as those measuring 9 and 4 micrometres. The proposed microfluidic device can be used for sorting RBCs and WBCs from whole blood sample","PeriodicalId":221953,"journal":{"name":"2022 3rd International Conference on Smart Electronics and Communication (ICOSEC)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MEMS based Chip for Blood Cell Sorting using Microfluidic Channel\",\"authors\":\"S. Ramya, S. Praveen Kumar, T. K. Srinivasan, T. Aravind, G. Ram, D. Lingaraja\",\"doi\":\"10.1109/ICOSEC54921.2022.9952048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hydraulic jump concept is used to separate and capture blood cells in this study. The two-dimensional microfluidic simulation model is used to create the devices. In many medical tests, physical features of cells of interest, such as size, deformability, and electric and magnetic properties, have become more important because of the inherent difficulties of isolation techniques based on biomarkers and antigens. In this study, cell/particle sorting in microchannels is investigated by using the inherent hydrodynamic effects. Microfluidic hydraulic jumps may be induced by turning high-speed flow in a microfluidic channel into a flow that has high potential energy by varying the channel height, much as in macrofluidics. Cells of varying sizes have their own chambers, such as those measuring 9 and 4 micrometres. The proposed microfluidic device can be used for sorting RBCs and WBCs from whole blood sample\",\"PeriodicalId\":221953,\"journal\":{\"name\":\"2022 3rd International Conference on Smart Electronics and Communication (ICOSEC)\",\"volume\":\"14 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2022 3rd International Conference on Smart Electronics and Communication (ICOSEC)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICOSEC54921.2022.9952048\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2022 3rd International Conference on Smart Electronics and Communication (ICOSEC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICOSEC54921.2022.9952048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
MEMS based Chip for Blood Cell Sorting using Microfluidic Channel
Hydraulic jump concept is used to separate and capture blood cells in this study. The two-dimensional microfluidic simulation model is used to create the devices. In many medical tests, physical features of cells of interest, such as size, deformability, and electric and magnetic properties, have become more important because of the inherent difficulties of isolation techniques based on biomarkers and antigens. In this study, cell/particle sorting in microchannels is investigated by using the inherent hydrodynamic effects. Microfluidic hydraulic jumps may be induced by turning high-speed flow in a microfluidic channel into a flow that has high potential energy by varying the channel height, much as in macrofluidics. Cells of varying sizes have their own chambers, such as those measuring 9 and 4 micrometres. The proposed microfluidic device can be used for sorting RBCs and WBCs from whole blood sample