定量超声成像变化作为乳腺癌患者对新辅助化疗反应的预测因子

H. Piotrzkowska-Wróblewska, K. Dobruch-Sobczak, M. Gumowska, J. Litniewski
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引用次数: 1

摘要

本研究证明了定量超声成像(h -扫描超声)在监测乳腺癌对新辅助化疗的反应和预测病理反应方面的有效性。一组40名患者(51名乳腺肿瘤患者)参与了这项研究。结果表明,QUS成像能够在治疗过程的早期区分对化疗有反应和无反应的乳腺癌患者。分析参数图像中红色的变化百分比,该参数可以预测患者在第1次、第2次、第3次、第4次给药后1周的受试者工作特征(ROC)曲线下面积分别为0.61、0.70、0.83、0.86。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes in quantitative ultrasound imaging as the predictor of response to neoadjuvant chemotherapy in patients with breast cancer
The presented study demonstrates the effectiveness of quantitative ultrasound imaging (H-scan ultrasound) in monitoring the breast cancer response to neoadjuvant chemotherapy and predicting pathological response. A group of 40 patients (51 breast tumors) participated in the study. The results showed that QUS imaging was able to distinguish between breast cancer patients responding and not responding to chemotherapy early in the course of treatment. Analysis of the percentage changes in red in the parametric images showed that this parameter can predict the response to treatment of patients with the area under the receiver operational characteristics (ROC) curve of 0.61, 0.70, 0.83, and 0.86, respectively, one week after 1st, 2nd, 3rdand 4th dose of treatment.
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