{"title":"腺嘌呤阿拉伯糖苷(Ara-A)的致畸性。","authors":"A R Gasset, T Akaboshi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The potentially teratogenic effect of antiviral drugs, particularly when given systemically, prompted the evaluation of the teratogenic effect of Ara-A when given systemically in doses significantly higher than those used clinically. Under the conditions of this study, neither teratogenic nor embryocidal effects of Ara-A were observed.</p>","PeriodicalId":14844,"journal":{"name":"Investigative ophthalmology","volume":"15 7","pages":"556-7"},"PeriodicalIF":0.0000,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Teratogenicity of adenine arabinoside (Ara-A).\",\"authors\":\"A R Gasset, T Akaboshi\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The potentially teratogenic effect of antiviral drugs, particularly when given systemically, prompted the evaluation of the teratogenic effect of Ara-A when given systemically in doses significantly higher than those used clinically. Under the conditions of this study, neither teratogenic nor embryocidal effects of Ara-A were observed.</p>\",\"PeriodicalId\":14844,\"journal\":{\"name\":\"Investigative ophthalmology\",\"volume\":\"15 7\",\"pages\":\"556-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1976-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Investigative ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Investigative ophthalmology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The potentially teratogenic effect of antiviral drugs, particularly when given systemically, prompted the evaluation of the teratogenic effect of Ara-A when given systemically in doses significantly higher than those used clinically. Under the conditions of this study, neither teratogenic nor embryocidal effects of Ara-A were observed.