{"title":"角膜糖原合成。牛肉角膜糖异生途径的证据。","authors":"S Andrews","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Beef eye anterior chambers were perfused with media containing radiolabeled glycogen precursors. Incorporation of 14C from 1-alanine-U-14C into corneal epithelium glycogen suggested the presence of a gluconeogenic pathway in the eye. Failure to isolate radioactive glucose from 1-alanine-U-14C-containing perfusate after passage through the anterior chamber strongly suggests a corneal site for this pathway.</p>","PeriodicalId":14844,"journal":{"name":"Investigative ophthalmology","volume":"15 7","pages":"542-6"},"PeriodicalIF":0.0000,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Corneal glycogen synthesis. I. Evidence for a gluconeogenic pathway in beef cornea.\",\"authors\":\"S Andrews\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Beef eye anterior chambers were perfused with media containing radiolabeled glycogen precursors. Incorporation of 14C from 1-alanine-U-14C into corneal epithelium glycogen suggested the presence of a gluconeogenic pathway in the eye. Failure to isolate radioactive glucose from 1-alanine-U-14C-containing perfusate after passage through the anterior chamber strongly suggests a corneal site for this pathway.</p>\",\"PeriodicalId\":14844,\"journal\":{\"name\":\"Investigative ophthalmology\",\"volume\":\"15 7\",\"pages\":\"542-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1976-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Investigative ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Investigative ophthalmology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
牛眼前房灌注含有放射性标记糖原前体的介质。来自1-丙氨酸- u -14C的14C掺入角膜上皮糖原表明眼睛中存在糖异生途径。通过前房后,不能从含1-丙氨酸- u - 14c的灌注液中分离出放射性葡萄糖,强烈提示该途径存在于角膜部位。
Corneal glycogen synthesis. I. Evidence for a gluconeogenic pathway in beef cornea.
Beef eye anterior chambers were perfused with media containing radiolabeled glycogen precursors. Incorporation of 14C from 1-alanine-U-14C into corneal epithelium glycogen suggested the presence of a gluconeogenic pathway in the eye. Failure to isolate radioactive glucose from 1-alanine-U-14C-containing perfusate after passage through the anterior chamber strongly suggests a corneal site for this pathway.