新的甲氧基活性单吲哚和双吲哚化合物的合成

Hakan Kandemir
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引用次数: 1

摘要

以4,6-二甲氧基-2,3-二苯基吲哚-7-乙醛与水合肼为起始原料,采用希夫碱反应条件成功合成了吲哚腙。该化合物与丙酮反应生成吲哚基亚胺化合物。通过质谱、1H谱和单晶x射线衍射技术鉴定了目标化合物的结构。同时,将双吲哚与n -溴琥珀酰亚胺进行溴化反应,得到相应的溴双吲哚衍生物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
An indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate. The reaction of this compound with acetone yielded indole based imine compound. The structure of targeted compound was identified by mass and 1H spectroscopy along with single crystal X-ray diffraction technique. Also, bromination of bis-indole with N-bromo succinimide was produced corresponding bromo bis-indol derivative.
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