JC Atenco-Cuautle, T. Spezzia-Mazzocco, R. Ramos-García, J. Ramirez-San-Juan, J. Ramirez-Ramirez, M. Delgado-López
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Methylene blue as a photosensitizer in the photodynamic therapy of breast cancer cell lines
We compared MB-PDT effect on two breast cancer cell lines: MDA-MB-231 from a triple negative adenocarcinoma, and T47D from a ductal cell tumor of woman. Methylene blue concentrations at 5, 10 and 20 μM and red light doses of 20, 40 and 60 J/cm2 were employed. Cell viability was evaluated with the MTT test, obtaining around 80% of inhibition with 20 μM and 60 J/cm2 of light dose.
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