从计算角度分析营养状况对耐药性的影响

Zakir Hussain, M. Borah
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引用次数: 0

摘要

如今,耐药性正在以非常快的速度增长。导致我们体内产生耐药性的原因有很多。但是,最常见的原因是遗传条件、病原体突变、其他药物的副作用和药物滥用。我们身体的营养状况在对抗耐药性的发展中起着重要的作用。在这项研究中,我们使用计算方面来分析营养状况对耐药性的影响。我们将营养不足、营养正常、营养过剩这三种营养状态都用在了与耐药性相关的方程式中。我们的实验结果表明,营养不足的情况急剧促进了耐药性的发展,正常营养有意地控制了耐药性,而过度营养促进了耐药性,但比营养不足要好。这些结果清楚地表明营养状况对耐药性的影响符合临床预期。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Computational Aspect to Analyse Impact of Nutritional Status on Drug Resistance
Drug resistance is increasing with a very fast rate now-a-days. There are a lot of reasons that lead to drug resistance in our body. But, the most common reasons are Genetic conditions, Mutation of the pathogen, Side effects of other medications, and Medicinal abuse. Nutritional status of our body has significant role in combating the development of drug resistance. In this study, we use a computational aspect to analyse the impact of nutritional status on drug resistance. We use all the three situations of nutritional status like under-nutrition, normal-nutrition, and over-nutrition in the formulation of equations to relate drug resistance. Our experimental results show that the situation of under-nutrition sharply boosts the development of drug resistance, normal-nutrition deliberately controls the drug resistance while over-nutrition boost the drug resistance but it is better compared to under-nutrition. These results clearly show the impact of nutritional status on drug resistance at par clinical expectations.
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