会阴瘘伴肛门腺鳞癌1例

A. Hajri, Abderrahmane Lamnaouar, Kabira Falousse, Driss Erreguibi, R. Boufettal, El Jay Saad Rifki, Chehab Farid
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引用次数: 0

摘要

简介:肛门腺鳞癌(ASC)是一种罕见的结直肠肿瘤,具有腺状和鳞状的组织病理特征。病例介绍:一名63岁男性,有一年的间歇性直肠疼痛和会阴瘘出血史。手术标本病理分析显示为肛门腺鳞癌,患者接受化疗和放疗的新辅助治疗,为期5周。然后他接受了腹部会阴切除术和永久性结肠造口术。组织学显示切除标本上浸润性腺鳞癌,患者开始接受FOLFIRINOX辅助治疗。讨论:原发性结肠和直肠ASC是极为罕见的临床疾病,预后较差。大多数数据来自个别病例报告和少数小系列,这使得了解该疾病的组织发生成为一项挑战。治疗方式还没有很好地编纂,这对总体生存有影响。结论:早期诊断和根治性手术配合其他可行的治疗方式可改善临床疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anal adenosquamous carcinoma on perineal fistula: A case report
Introduction: Adenosquamous Carcinoma (ASC) of the anus presenting both glandular and squamous histopathologic features is a rare colorectal neoplasm. Case presentation: A 63-year-old man presented with a one-year history of intermittent rectal pain and bleeding on a perineal fistula. Pathological analysis of the surgical specimen revealed adenosquamous carcinoma of the anus, The patient received neoadjuvant treatment with chemotherapy and radiotherapy over a period of five weeks. then he underwent abdominoperineal resection and a permanent colostomy. Histology revealed invasive adenosquamous carcinoma on the resection specimen and the patient was started on adjuvant therapy with FOLFIRINOX. Discussion: Primary ASC of the colon and rectum are extremely rare clinical entities with poor prognosis. Most of the data come from individual case reports and a few small series, making it a challenge to understand the histogenesis of the disease. And the treatment modalities are not yet well codified, which has an impact on overall survival. Conclusion: Early diagnosis and radical surgery with other available therapeutic modalities can improve clinical outcomes.
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