重组ZIKV包膜蛋白用于虫媒病毒病的ELISA鉴别诊断

Juliana Freitas, P. Terra, J. Gonçalves, M. G. Cavalcanti, M. Castro, R. H. Peralta, J. M. Peralta
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引用次数: 0

摘要

寨卡病毒是黄病毒科的一种虫媒病毒,可引起无症状和有症状感染。在这些病毒共循环的地区,虫媒病毒的临床诊断是困难的,因此,基于宿主免疫反应的实验室确认是重要的,特别是对孕妇。使用重组蛋白作为抗原的目的是提高免疫检测的敏感性和特异性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recombinant ZIKV envelope proteins for the arbovirosis differential diagnosis by ELISA
Introduction: The Zika virus is an arbovirus of the Flaviviridae family that causes asymptomatic and symptomatic infections. The clinical diagnosis of arboviroses is difficult in areas with cocirculation of these viruses and, therefore, laboratory confirmation based on host immune response is important, especially for pregnant women. The use of recombinant proteins as antigens aims to improve the sensitivity and specificity of the immunological test.
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