玻璃体内注射贝伐单抗治疗视网膜分支静脉闭塞的黄斑水肿

W. Ewais, M. ElShazly, A. A. Nossair
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引用次数: 0

摘要

目的:目的是评估玻璃体内贝伐单抗(IVB)治疗因视网膜分支静脉阻塞(BRVO)引起的黄斑水肿(ME)的视觉和解剖学结果。方法:回顾性,连续病例系列。对26例患者的26只眼进行了研究。结果测量包括:最佳矫正视力(BCVA),光谱域光学相干断层扫描的中央黄斑厚度(CMT)和并发症。结果:在6.9个月(4-12个月)的随访期间,BCVA从最初的平均BCVA: 0.1(计数手指:1 m-0.3)提高到平均BCVA 0.4(0.05-0.8),平均改善了3.2行。CMT从初始平均值613 (401 ~ 959 μ)降至随访结束时的平均值400 μ (274 ~ 623 μ)。无并发症记录。这是通过平均注射次数实现的:4次注射范围(3-6次注射)。结论:IVB是治疗BRVO继发ME的有效方法。在许多病例中,VA显著改善,黄斑厚度显著减少,但并非所有病例都如此。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intravitreal bevacizumab injection for management of macular edema in branch retinal vein occlusion
Purpose: The aim was to evaluate visual and anatomical outcome of intravitreal bevacizumab (IVB) in eyes with macular edema (ME) due to branch retinal vein occlusion (BRVO). Methods: Retrospective, consecutive case series. Study was done on 26 eyes of 26 patients. Outcome measures include: Best corrected visual acuity (BCVA), central macular thickness (CMT) by spectral domain optical coherence tomography, and complications. Results: BCVA improved by a mean of 3.2 lines from an initial mean BCVA: 0.1 (counting fingers: 1 m-0.3) to a mean BCVA 0.4 (0.05-0.8) over the follow-up period of 6.9 months (4-12 months). CMT was reduced from an initial mean of 613 (401-959 μ) to the mean of 400 μ (274-623 μ) at the end of the follow-up period. No complications were recorded. This was achieved through a mean number of injections: Four with a range (3-6 injections). Conclusion: IVB is an effective treatment for ME secondary to BRVO. There was a significant improvement of VA and significant reduction in macular thickness in many cases, but not in all cases.
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