P5‐42:斯里兰卡三级医疗医院使用风险评估工具评估暴露于COVID‐19的医护人员的结果和风险分类

Respirology (Carlton, Vic.) Pub Date : 2021-11-01 DOI:10.1111/resp.14150_249

W. Kami, W. Arakaki, Hiroe, Hashioka, H. Oki, D. Motooka, Shota, Nakamura, J. Fujita, S. Ranasinghe, Geetha., Nanayakkara, G. L. A. Lakruwan, A. Ranasinghe, Lalith Abeywardhane, B. Rathnayake, Santh, Jayasinghe, U. Rathnayake, A. Rodrigo, L. Dassanayake, A. Fernando, A. Sadikeen, G. Somasundaram

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引用次数: 0

摘要

pital。尸检发现脑、肺、心、肾上腺、肾等多器官出现坏死结节、血栓性血管炎和出血梗塞。在这些器官的血管内观察到许多丝状真菌，中性粒细胞明显浸润。Grocott菌株和遗传分析表明该真菌属于小孢子根霉属。我们的结论是，他死于败血症和多器官功能衰竭，由于播散性毛霉病。虽然类固醇和IL-6抑制剂能提高重症Covid-19感染患者的生存率，但在对Covid-19感染的高免疫进行强效免疫抑制治疗时，可能会出现播散性真菌感染等严重机会性感染。

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P5‐42: Assessment of outcome and risk categorization of COVID‐19 exposed healthcare workers using a risk assessment tool in a Tertiary Care Hospital, Sri Lanka

pital. Autopsy revealed necrotic nodules, thromboangitis and hemorrhage infarction in multiple organs including brain, lung, heart, adrenal gland and kidney. Many filamentous fungi with prominent infiltration of neutrophils were observed intravascularly in these organs. Grocott strain and genetic analysis revealed that the fungi belong to Rhizopus microsporus group. We concluded that he died of sepsis and multiple organ failure due to disseminated mucormycosis. Though steroids and IL-6 inhibitor improve survival rate of severe Covid-19 infection, it should be considered severe opportunistic infection such as disseminated fungal infection might occur under the powerful immunosuppressive treatment to modulate hyperimmunity due to COVID-19 infection.

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Respirology (Carlton, Vic.)

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