Evaluation of Effectiveness of Concentrated Growth Factors on Osseointegration Around Immediate Dental Implant

Aim: This study was designed to evaluate of using concentrated growth factors membrane (CGF) membrane mixed with concentrated growth factors (CGF) sticky bone around immediate implant versus immediate implant placement without any addition in mandibular molar area. Subjects and Methods: Twelve implant fixtures were inserted in 12 patients divided equally into two groups. The patients were selected from those attending outpatient clinic, Oral and Maxillofacial Surgery Department, at the Faculty of Dental Medicine, Cairo, Al-Azhar University (Cairo, Boys). Clinical examination was made to all patients by measuring of primary stability at time of implant placement and 6 months after implant placement as a secondary stability by ossttel device, Preoperative and after 6 months postoperatively cone beam CT for every patient to determine bone density between bony walls and implant surfaces. Data were collected, revised, coded and entered to the Statistical Package for Social Science (IBM SPSS) version 23. Results: The mean crestal bone resorption value in mesial and distal side of immediate implant placement with concentrated growth factor CGF membrane with CGF sticky bone around implant was 0.09±0.03mm & 0.43±0.23mm contrary to the immediate implant without any addition after 6 months follow up, which was 0.33±0.14mm & 1.56±0.77mm which was statistically significant.  Conclusion: Immediate implant placement with CGF membrane/ CGF sticky bone show significant increase in secondary stability after six months.