{"title":"处理诱发癫痫对沙鼠被动回避学习的影响","authors":"Amy Rothman Schonfeld, Stanley D. Glick","doi":"10.1016/S0091-6773(78)92971-1","DOIUrl":null,"url":null,"abstract":"<div><p>The effect of handling-induced seizures on passive avoidance behavior was investigated in the gerbil. In the first experiment, ictal activity immediately before Day 1 training significantly impaired retention on Day 2; after additional training on Day 2, retention was normal on Day 3. In the second experiment, a 24-hr interval was allowed between seizure testing and passive avoidance training. No difference between seizing and nonseizing groups was seen during the Day 2 training or Day 3 retention trials. Therefore, the Day 2 impairment in the first experiment was attributed to the immediate effect of the seizure on Day 1 learning. It was suggested that the poor performance of some gerbils in passive avoidance may be attributed to pretraining ictal activity.</p></div>","PeriodicalId":75577,"journal":{"name":"Behavioral biology","volume":"24 1","pages":"Pages 101-106"},"PeriodicalIF":0.0000,"publicationDate":"1978-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0091-6773(78)92971-1","citationCount":"7","resultStr":"{\"title\":\"Effect of handling-induced seizures on passive avoidance learning in the Mongolian gerbil (Meriones unguiculatus)\",\"authors\":\"Amy Rothman Schonfeld, Stanley D. Glick\",\"doi\":\"10.1016/S0091-6773(78)92971-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The effect of handling-induced seizures on passive avoidance behavior was investigated in the gerbil. In the first experiment, ictal activity immediately before Day 1 training significantly impaired retention on Day 2; after additional training on Day 2, retention was normal on Day 3. In the second experiment, a 24-hr interval was allowed between seizure testing and passive avoidance training. No difference between seizing and nonseizing groups was seen during the Day 2 training or Day 3 retention trials. Therefore, the Day 2 impairment in the first experiment was attributed to the immediate effect of the seizure on Day 1 learning. It was suggested that the poor performance of some gerbils in passive avoidance may be attributed to pretraining ictal activity.</p></div>\",\"PeriodicalId\":75577,\"journal\":{\"name\":\"Behavioral biology\",\"volume\":\"24 1\",\"pages\":\"Pages 101-106\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1978-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0091-6773(78)92971-1\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Behavioral biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0091677378929711\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioral biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0091677378929711","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of handling-induced seizures on passive avoidance learning in the Mongolian gerbil (Meriones unguiculatus)
The effect of handling-induced seizures on passive avoidance behavior was investigated in the gerbil. In the first experiment, ictal activity immediately before Day 1 training significantly impaired retention on Day 2; after additional training on Day 2, retention was normal on Day 3. In the second experiment, a 24-hr interval was allowed between seizure testing and passive avoidance training. No difference between seizing and nonseizing groups was seen during the Day 2 training or Day 3 retention trials. Therefore, the Day 2 impairment in the first experiment was attributed to the immediate effect of the seizure on Day 1 learning. It was suggested that the poor performance of some gerbils in passive avoidance may be attributed to pretraining ictal activity.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
