硬膜外脊髓转移:与椎板减压切除术病例选择相关的因素。

M L Apuzzo, M H Weiss, H V Minassian
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摘要

我们选择了一系列脊髓硬膜外转移性肿瘤患者,根据我们认为会产生最有利的治疗效果的原则,采用背侧减压法进行治疗。无手术死亡率,发病率低。术后第一周,44%的患者运动功能明显改善。到术后3个月,40%的患者可以独立走动,另外28%的患者可以在最低限度的帮助下走动。这68%的综合结果优于30 - 40%的结果在几个系列的未选择的情况。基于这些数据,我们得出结论,考虑肿瘤的组织学类型、生物学史、宿主的反应、神经功能缺损的程度、神经功能缺损的进展和疾病的传播,将有助于确定那些硬膜外转移病例,这些病例可能会受益于手术减压。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidural spinal metastases: factors related to selection of cases for decompressive laminectomy.

We have treated a selected series of patients with spinal epidural metastatic tumors by dorsal decompression according to principles we presumed would produce the most favorable therapeutic results. There was no operative mortality, and morbidity was minor. In the first postoperative week, improvement in motor function was apparent in 44% of cases. By 3 months postoperatively, 40% of the patients were independently ambulatory and an additional 28% were ambulatory with minimal assistance. This 68% composite compares favorably to the 30 to 40% results in several series of unselected cases. On the basis of this data, it is concluded that consideration of the tumor's histological type, biological history, the host's response, the extent of neurological deficit, the progression of neurological deficit, and dissemination of disease will aid in the definition of those cases with epidural metastases which may be expected to benefit from surgical decompression.

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