急性乙醇中毒对颅内物理动力学的影响。

M H Weiss, J R Craig
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摘要

研究了42只成年猫急性乙醇中毒对颅内物理动力学的影响。急性乙醇中毒显著改变颅内组织顺应性,这是由颅内容积压反应决定的。继发于乙醇的脑血管扩张似乎是一种潜在的机制,可能因继发性脑水肿而增强。脑脊液的产生和吸收以及渗透比的研究显示急性乙醇中毒条件下没有变化。观察到的大脑依从性的降低很可能与酒精脑外伤的预后不良有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The influence of acute ethanol intoxication on intracranial physical dynamics.

The influence of acute ethanolic intoxication on intracranial physical dynamics was assessed in 42 adult cats. Acute ethanolism significantly alters intracranial tissue compliance as determined by the intracranial volume-pressure response. Cerebral vasodilatation, secondary to ethanol administration, appears to be an underlying mechanism, possibly augmented by secondary cerebral edema. Studies of CSF production and absorption as well as osmolar ratio show no changes under conditions of acute ethanol intoxication. The observed decrease in cerebral compliance may well relate to the poor prognosis, in general, of the alcoholic brain that is subjected to trauma.

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