{"title":"基于1,2-秒霉素的合成。第4部分。一个新的三环-内酰胺衍生物。","authors":"M J Pearson","doi":"10.1039/p19770000189","DOIUrl":null,"url":null,"abstract":"Heating (3R,4R)-1-[azido-(t-butoxycarbonyl)methyl]-4-(prop-2-ynylthio)-3-(triphenylmethylamino)azetidin-2-one (4) in refluxing toluene resulted in smooth intramolecular cycloaddition of the azido-group to the acetylenic function to afford (5aR,6R,9ξ,)-t-butyl 6,7-dihydro-7-oxo-6-triphenylmethylamino-4H,5aH-azeto[2,1-b]-v-triazolo[3,4-e][1,3,5]thiadiazepine-9-carboxylate (5).","PeriodicalId":17273,"journal":{"name":"Journal of the Chemical Society. Perkin transactions 1","volume":"2 ","pages":"189-92"},"PeriodicalIF":0.0000,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1039/p19770000189","citationCount":"20","resultStr":"{\"title\":\"Syntheses based on 1,2-secopenicillins. Part 4. A new tricyclic beta-lactam derivative.\",\"authors\":\"M J Pearson\",\"doi\":\"10.1039/p19770000189\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Heating (3R,4R)-1-[azido-(t-butoxycarbonyl)methyl]-4-(prop-2-ynylthio)-3-(triphenylmethylamino)azetidin-2-one (4) in refluxing toluene resulted in smooth intramolecular cycloaddition of the azido-group to the acetylenic function to afford (5aR,6R,9ξ,)-t-butyl 6,7-dihydro-7-oxo-6-triphenylmethylamino-4H,5aH-azeto[2,1-b]-v-triazolo[3,4-e][1,3,5]thiadiazepine-9-carboxylate (5).\",\"PeriodicalId\":17273,\"journal\":{\"name\":\"Journal of the Chemical Society. Perkin transactions 1\",\"volume\":\"2 \",\"pages\":\"189-92\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1977-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1039/p19770000189\",\"citationCount\":\"20\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Chemical Society. Perkin transactions 1\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1039/p19770000189\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Chemical Society. Perkin transactions 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/p19770000189","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Syntheses based on 1,2-secopenicillins. Part 4. A new tricyclic beta-lactam derivative.
Heating (3R,4R)-1-[azido-(t-butoxycarbonyl)methyl]-4-(prop-2-ynylthio)-3-(triphenylmethylamino)azetidin-2-one (4) in refluxing toluene resulted in smooth intramolecular cycloaddition of the azido-group to the acetylenic function to afford (5aR,6R,9ξ,)-t-butyl 6,7-dihydro-7-oxo-6-triphenylmethylamino-4H,5aH-azeto[2,1-b]-v-triazolo[3,4-e][1,3,5]thiadiazepine-9-carboxylate (5).
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
