J Tennvall, T Andersson, K Aspegren, A Biörklund, S Ingemansson, T Landberg, M Akerman
{"title":"未分化的甲状腺巨细胞癌和梭形细胞癌。两种联合治疗方式的报告。","authors":"J Tennvall, T Andersson, K Aspegren, A Biörklund, S Ingemansson, T Landberg, M Akerman","doi":"10.3109/02841867909128226","DOIUrl":null,"url":null,"abstract":"<p><p>Undifferentiated giant and spindle cell carcinoma of the thyroid is a rapidly fatal disease. Most patients die from local tumour progression and with distant metastases. A combination of debulking surgery, irradiation and combination chemotherapy is reported. An improvement of the local results of treatment was observed. A combination of irradiation and chemotherapy resulted in local control in only one of 8 patients. Therefore, debulking surgery was added in the next 5 patients and a local control was achieved in 4.</p>","PeriodicalId":75417,"journal":{"name":"Acta radiologica: oncology, radiation, physics, biology","volume":"18 5","pages":"408-16"},"PeriodicalIF":0.0000,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867909128226","citationCount":"21","resultStr":"{\"title\":\"Undifferentiated giant and spindle cell carcinoma of the thyroid. Report on two combined treatment modalities.\",\"authors\":\"J Tennvall, T Andersson, K Aspegren, A Biörklund, S Ingemansson, T Landberg, M Akerman\",\"doi\":\"10.3109/02841867909128226\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Undifferentiated giant and spindle cell carcinoma of the thyroid is a rapidly fatal disease. Most patients die from local tumour progression and with distant metastases. A combination of debulking surgery, irradiation and combination chemotherapy is reported. An improvement of the local results of treatment was observed. A combination of irradiation and chemotherapy resulted in local control in only one of 8 patients. Therefore, debulking surgery was added in the next 5 patients and a local control was achieved in 4.</p>\",\"PeriodicalId\":75417,\"journal\":{\"name\":\"Acta radiologica: oncology, radiation, physics, biology\",\"volume\":\"18 5\",\"pages\":\"408-16\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1979-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/02841867909128226\",\"citationCount\":\"21\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta radiologica: oncology, radiation, physics, biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/02841867909128226\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica: oncology, radiation, physics, biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841867909128226","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Undifferentiated giant and spindle cell carcinoma of the thyroid. Report on two combined treatment modalities.
Undifferentiated giant and spindle cell carcinoma of the thyroid is a rapidly fatal disease. Most patients die from local tumour progression and with distant metastases. A combination of debulking surgery, irradiation and combination chemotherapy is reported. An improvement of the local results of treatment was observed. A combination of irradiation and chemotherapy resulted in local control in only one of 8 patients. Therefore, debulking surgery was added in the next 5 patients and a local control was achieved in 4.
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