口腔药物相关性大疱性类天疱疮

N. Regmi, J. Rimal
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引用次数: 0

摘要

大疱性类天疱疮是一种自身免疫性皮肤病,其特征是大而紧张的水泡,孤立的口腔表现是罕见的。我们报告一例48岁男性,主诉为口腔左侧伤口,有使用氢氯噻嗪的历史。口腔内检查发现,腭龈有脱屑,触诊时触痛。组织病理学检查报告为口腔类天疱疮。免疫荧光检测发现C3和免疫球蛋白G呈线性沉积。这表明,完整的病史与组织病理学和免疫荧光试验的重要性是必须早期诊断和治疗是必不可少的,以防止进一步的皮肤病进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Drug associated bullous pemphigoid in oral cavity
Bullous pemphigoid is an autoimmune skin disease characterized by large tense blisters with solitary oral manifestation a rarity. We report a case of 48-year-old male with chief complain of wound on the left side of mouth with history of hydrochlorothiazide use. On intraoral examination, desquamation was present in palatal gingiva which was tender on palpation. Biopsy of the lesion on histopathology reported oral pemphigoid. On immunofluorescence test linear deposits of C3 and immunoglobulin G was found. This showed that importance of complete history with histopathology and immunofluorescence test is must for early diagnosis and treatment is essential for prevent further dermatological progression.
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