孟加拉国一家三级保健中心剖宫产术后部位感染的发生率、危险因素和微生物

Shahfinaz Mehzabin, M. Elahi, D. Bar, B. Sinha, T. Akter, N. Alam
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摘要

背景:手术部位感染(SSI)是剖宫产(c -剖宫产)术后常见的并发症,是导致产妇发病率增高和治疗费用增高的主要原因。本研究旨在确定达卡医学院医院(DMCH)剖宫产术后手术部位感染的发生率和危险因素。材料与方法:本研究为回顾性观察性研究,选取2019年1月至2019年12月在DMCH产后户外门诊就诊的剖腹产手术部位感染患者为研究对象。数据采用结构化问卷收集。以培养为基础的微生物学方法用于确定术后伤口的致病因子。结果:剖宫产术后SSI总发生率为4.44%。与患者相关的危险因素为产前检查不充分、急诊手术、营养不良(22.44%)、贫血(21.46%)、相关合并症(59.46%)、破膜史>12小时(40.98%)和分娩疼痛史>12小时(16.10%)。未经培训的接生员在每次阴道检查中重复手术相关危险因素(21.95%),手术时间>1小时(62.93%)。最常见的SSI病原菌为金黄色葡萄球菌44(21.46%)和大肠杆菌31(15.12%)。最敏感的抗生素是氨基糖苷类、头孢菌素和氯西林。结论:本研究发现的大部分剖宫产术后手术部位感染的危险因素都可以通过干预加以改善。然而,从我们的病人身上检测到的微生物显示出对我们设置的常用抗菌素的高度耐药性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence, risk factors and Microorganisms for post caesarean Surgical Site Infection In A Tertiary Care Centre in Bangladesh
Background: Surgical site infection (SSI) is a common complication following caesarean section (C-section) and mainly responsible for increased maternal morbidity and higher treatment costs. This study will determine the incidence and risk factors of surgical site infections following caesarean section in Dhaka Medical College Hospital (DMCH). Materials and Methods: This is a retrospective observational study which was conducted among patients having post caesarean surgical site infections attending post-natal outdoor clinic of DMCH from January, 2019 to December, 2019. Data were collected in structured questionnaire. Culturebased microbiological methods were used to identify causal agents in postoperative wounds. Results: Overall SSI rate following caesarian section was 4.44%.Patient related risk factors were inadequate antenatal check-up, emergency procedures, malnutrition (22.44%), anaemia (21.46%) associated comorbidity (59.46%), history of rupture membrane >12 hours (40.98%) and had history of prolonged labour pain >12 hours (16.10%).Surgery related risk factors were repeated per vaginal examinations by untrained birth attendant (21.95%) & duration of surgery>1 hour (62.93%). The most common organisms responsible for SSI were Staphylococcus aureus 44(21.46%) and Escherichia coli 31(15.12%). The most sensitive antibiotics were aminoglycosides, cephalosporin & cloxacillin. Conclusion: Most of the risk factors for surgical site infection following caesarean section identified in this study can be modified through intervention. However the microorganisms detected from our patient showed a high degree of resistance for commonly prescribed antimicrobials in our set-up.
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