三种局部左心室泵模型的描述能力

A. Cappello, G. Avanzolini
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引用次数: 1

摘要

本文提出了左心室(LV)泵送功能的三种粘弹性模型,并与经典的弹性-阻力描述进行了比较,这些描述是从狗身上测量的数据开始的:给定预负荷下的等容压,以及一系列左心室压力和分级主动脉闭塞的流出曲线。比较标准考虑了描述能力、估计的稳健性和它们的物理解释。分析证实了活化和失活现象的存在。刚度和阻力对后载荷的依赖性与已知心肌特征一致,支持了所提模型的局部有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Descriptive ability of three local left ventricle pump models
Three viscoelastic models of the left-ventricular (LV) pumping function are proposed and compared with the classical elastance-resistance description starting from data measured on dogs: isovolumic pressure at a given preload together with a series of LV pressure and outflow curves with graded aortic occlusions. The comparison criterion takes into account descriptive ability, robustness of the estimates, and their physical interpretation. The analysis confirms the presence of both activation and deactivation phenomena. The dependence of stiffness and resistance on afterload agrees with known myocardial features and supports the local validity of the proposed models.<>
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