Sabrina Shafiq, Mohammad Nuruzzaman Khan, Bipasha Majumder, Mohammad Shahinul Alam, M. Islam, T. Sultana
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引用次数: 2
摘要
肝硬化的特点是正常肝组织被瘢痕组织取代。child - turcote - pugh (CTP)评分用于评估肝硬化的预后,包括总胆红素水平、血清白蛋白、凝血酶原时间、腹水和肝性脑病5个因素。CTP评分取决于临床评估,这可能导致评分的变化。近年来引入了一种新的评分方法,即白蛋白-胆红素(ALBI)评分,可以代替肝硬化患者的CTP评分。该横断面研究于2018年3月至2019年2月在检验医学系与达卡BSMMU肝脏内科合作进行。对81例肝硬化患者的血液样本进行了分析。所有统计分析均使用SPSS version 22。研究组平均年龄46.1±16.0岁。男性占64.2%,女性占35.8%。ALBI与CTP评分的Kappa (k)值为0.759。Pearson相关系数(r)检验显示CTP评分与ALBI评分呈正相关(r=+0.853, p<0.001)。本研究认为,肝硬化患者使用ALBI评分可以替代CTP评分,因为它简单,只有两个参数,更有证据基础,更客观。
"Correlation of Albumin-Bilirubin (ALBI) Score with Child-Turcotte-Pugh (CTP) Score in the Evaluation of Liver Cirrhosis "
Cirrhosis of liver is characterized by the replacement of normal liver tissue by scar tissue. The Child-Turcotte-Pugh (CTP) score is used to assess the prognosis of cirrhosis and included five factors: total bilirubin level, serum albumin, prothrombin time, ascites and hepatic encephalopathy. CTP score depends on clinical assessment which may result variation in scoring. Recently a new score is introduced, Albumin-Bilirubin (ALBI) score which may be done instead of CTP scoring in cirrhotic patient. This cross sectional study was conducted at the Department of Laboratory Medicine in collaboration with the Department of Hepatology, BSMMU, Dhaka, from March 2018 to February 2019. Blood samples were assayed from eighty one diagnosed cirrhotic patients. For all statistical analysis SPSS version 22 was used. The mean age of the study group was 46.1±16.0 years. 64.2% were male and 35.8% were female. Kappa (k) value was 0.759 between ALBI and CTP score. Pearson's correlation coefficient (r) test showed significant strong positive correlation between CTP score and ALBI score (r=+0.853, p<0.001). This study concluded that the ALBI score may be done alternative to the CTP score in cirrhotic patient because it’s simple, two parameters only, more evidence based and more objective.