糖尿病的体重管理、微量营养素和补充剂

E. Roberts, J. Mechanick
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引用次数: 0

摘要

今年在希腊阿纳维索斯举行的第39届糖尿病与营养国际研讨会举办了一系列专题介绍和全体讲座,重点是减肥、微量营养素、营养补充剂和替代饮食模式在预防和管理2型糖尿病(T2D)和减少心血管风险方面的影响。Michael Lean讨论了如何通过使用低能量饮食(LED)或极低能量饮食(VLED)减肥来缓解糖尿病,并辅以专业医疗保健专业人员的持续长期支持。Jeffrey Mechanick讨论了早期干预对T2D和心血管疾病(CVD)的重要性和影响。他强调,T2D不应该仅仅在发病时被发现,还应该在从糖尿病前期到并发症的范围内被发现,早期干预不仅对T2D的进展有重大影响,而且对后期阶段也有重大影响。刘思敏提出了一个综合的多层次框架,用于个性化心脏代谢健康的因果推理,重点介绍了最近研究膳食矿物质、环境金属和基因组学在心血管疾病和糖尿病中的作用。一些介绍包括对具体干预措施的讨论。Daniel West讨论了乳清蛋白(WP)的使用,以及它如何帮助控制口服抗高血糖药物控制的t2dm患者餐后血糖漂移(PGE)。随后,Andrea Hawkinson讨论了一种新的补充剂桑叶(Morus alba)提取物(MLE)如何显著降低餐后葡萄糖反应以及早期胰岛素反应,强调需要进一步研究以评估其对t2dm患者的疗效。菲利普·阿瑟顿(Philip Atherton)的研究提供了证据,证明补充蛋白质和必需氨基酸(EAA)有助于增加肌肉质量,这对患有糖尿病和肌肉减少症的老年人尤其重要。最后,Jose-María López-Pedrosa谈到了一种含有慢消化碳水化合物(SDC)、精氨酸、赖氨酸和β-羟基-β-甲基丁酸(HMB)的补充剂如何在糖尿病大鼠模型中帮助保持肌肉质量,并改善胰岛素抵抗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Weight Management, Micronutrients, and Supplements in Diabetes
This year’s 39th International Symposium on Diabetes and Nutrition in Anavyssos, Greece, hosted a series of presentations and plenary lectures with a focus on the effects of weight loss, micronutrients, nutritional supplements, and alternative dietary patterns in the prevention and management of Type 2 diabetes (T2D) and cardiovascular risk reduction. Michael Lean discussed how diabetes remission can be achieved through weight loss using a low-energy diet (LED) or very low-energy diet (VLED), accompanied by continued long-term support from specialised healthcare professionals. Jeffrey Mechanick discussed the importance and impact of early intervention on T2D and cardiovascular disease (CVD). He emphasised that T2D should be seen not just at the point of disease, but on a spectrum from prediabetes to complications, with early interventions having significant impact on not only the progression of T2D, but also into the latter stages.Simin Liu presented an integrative multilevel framework for causal inference to personalise cardiometabolic health, highlighting recent work investigating the roles of dietary minerals, environment metals, and genomics in relation to cardiovascular disease and diabetes. Several of the presentations included discussion of specific interventions. Daniel West discussed the use of whey protein (WP) and how it can help control postprandial glycaemic excursions (PGE) in people with T2D controlled on oral antihyperglycaemic drugs. Following this, Andrea Hawkinson discussed how a new supplement, mulberry leaf (Morus alba) extract (MLE), can significantly lower postprandial glucose response, as well as early insulin response, highlighting the need for further studies to evaluate its efficacy in people with T2D. Philip Atherton showed studies providing evidence that protein and essential amino acid (EAA) supplementation can help support muscle mass, which is especially essential for older people with T2D and sarcopenia. Finally, Jose-María López-Pedrosa spoke about how a supplement containing slow digestible carbohydrates (SDC), arginine, lysine, and β-hydroxy-β-methylbutyric acid (HMB) can help preserve muscle mass, as well as improve insulin resistance, in a rat model of diabetes.
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