生物分子电化学传感的有源CMOS阵列

2007 IEEE Custom Integrated Circuits Conference Pub Date : 2007-09-01 DOI:10.1109/CICC.2007.4405855

P. Levine, P. Gong, K. Shepard, R. Levicky

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引用次数: 7

摘要

我们设计了一种用于0.25 μ m cmos工艺中多路电化学生物分子检测的4times4有源传感器阵列。集成的电位器能感应到芯片表面发生的反应所产生的流过片上金电极的电流。初步实验结果包括几种氧化还原物质的循环伏安法和应用于DNA探针覆盖表征。

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Active CMOS Array for Electrochemical Sensing of Biomolecules

We describe the design of a 4times4 active sensor array for multiplexed electrochemical biomolecular detection in a 0.25-mum-CMOS process. Integrated potentiostats sense the current flowing through the on-chip Au electrodes that result from reactions occurring at the chip surface. Preliminary experimental results include cyclic voltammetry of several redox species and application to DNA probe coverage characterization.

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2007 IEEE Custom Integrated Circuits Conference

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