[糖尿病代谢条件下铅和一氧化碳的影响(作者译)]。

Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, Betriebshygiene, praventive Medizin Pub Date : 1979-06-01

H W Schlipköter, M Klitzke, J Unnewehr

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摘要

采用nzo -小鼠，研究了一氧化碳和铅对糖尿病代谢的影响。用80 ppm (COHb 10.81)处理的动物对葡萄糖的耐受性明显降低。即使在去除一氧化碳负担50天后，实验动物糖耐量试验后的血糖水平仍显著高于对照组(20 min值)。经肠内铅暴露的nzo -小鼠葡萄糖耐量试验后糖尿病代谢状况无明显变化。然而，与NMRI小鼠和大鼠相比，nzo小鼠的血糖水平明显更高。

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[Effect of lead and carbon monoxide under the condition of diabetic metabolism (author's transl)].

The NZO-Mice were used to study the influence of carbon monoxide and lead under the condition of diabetic metabolism. The animals treated with 80 ppm (COHb 10.81) showed significantly lower tolerance for glucose. Even after removing the burden of carbon monoxide for 50 days, the blood sugar level after glucose tolerance test remained in experimental animals significantly higher than in controls (20-min-value). The NZO-Mice after enteral lead exposition showed no significant changes of the condition of the diabetic metabolism after the glucose tolerance test. However, the NZO-Mice, compared to NMRI mice and rats, reached significantly higher level of blood sugar.

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Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, Betriebshygiene, praventive Medizin

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