糖尿病患者新型冠状病毒感染的诊断、病程及预后预测

A. Volynkina, Yu.V. Khodarina, P. I. Kazakova, E. A. Volynkina, N. Naumova, I. O. Elizarova
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摘要

介绍。到2023年,已发现6亿多例COVID-19病例。新型冠状病毒感染(NCVI)严重病程的最重要危险因素之一是合并症的存在,特别是糖尿病(DM)的存在。研究糖尿病患者新型冠状病毒感染的实验室和临床特征,以确定COVID-19不良结局的预测因素。材料和方法。我们从“沃罗涅日第10临床急救医院”的“COVID-5”和“COVID-8”部门的248名患者的病历中获取数据。采用Microsoft Excel 10.0和StatSoft STATISTICA 12.0软件进行数据收集和统计处理。患者最常见的主诉是全身乏力、高热和干咳。年龄特征分析显示,非糖尿病住院患者NCVI发病率高峰在70 ~ 79岁,合并糖尿病住院患者nvi发病率高峰在60 ~ 69岁。合并症以高血压、冠心病和慢性心力衰竭为主。这些疾病的存在与脑血管疾病和贫血一起是NCVI不良结局的预测因子。对实验室数据的评估显示铁蛋白、c反应蛋白和d -二聚体水平升高与ncvi死亡风险增加有关。估计致命结果的危险因素对患者治疗策略的选择至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Some aspects of diagnosis, course and prediction of outcomes of a new coronavirus infection in patients with diabetes mellitus
Introduction. By 2023 it has been detected more than 600 million cases of COVID-19. One of the most significant risk factors for the severe course of a new coronavirus infection (NCVI) is the presence of comorbid diseases, especially the presence of diabetes mellitus (DM).Aim. To investigate the laboratory and clinical features of a new coronavirus infection in people with diabetes mellitus, to identify predictors of an adverse outcome of COVID-19.Material and methods. We carried out data from medical records of 248 patients treated in “Voronezh Clinical Emergency Hospital № 10” in the departments “COVID-5” and “COVID-8”. Data collection and statistical processing were performed with Microsoft Excel 10.0 and StatSoft STATISTICA 12.0 programs.Results. The most frequent complaints of patients were general weakness, hyperthermia and dry cough. The analysis of the age characteristics revealed that the peak incidence of NCVI in hospitalized patients without DM falls on 70-79 years, with concomitant DM — on 60-69 years.Among comorbid pathologies, hypertension, coronary heart disease and chronic heart failure prevailed. The presence of these diseases is a predictor of adverse outcomes in NCVI, along with cerebrovascular diseases and anemia.Evaluation of laboratory data revealed the link of elevated levels of ferritin, C-reactive protein and D-dimer with an increased risk of death of NCVI.Conclusion. Estimation the risk factors of a fatal outcome is crucial for the choice of patient treatment tactics.
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