补料分批发酵过程的最优控制计算方法

R. Tzoneva
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引用次数: 1

摘要

提出并解决了酵母生产补料分批发酵过程的最优控制问题。该问题基于发酵结束时最大生物量产量的标准和非结构化质量平衡生物模型,该模型将物理化学变量作为控制输入纳入动力学系数。在拉格朗日增广泛函的基础上,提出了求解两级计算结构问题的分解方法。编写了计算程序,并将其应用于酵母补料间歇生产过程
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Method for Optimal Control Calculation of a Fed-batch Fermentation Process
A problem for optimal control of a fed-batch fermentation process for production of yeast is formulated and solved. The problem is based on a criterion for maximum production of biomass at the end of fermentation and on an unstructured mass balance biological model incorporating in the kinetic coefficients the physiochemical variables considered as control inputs. A decomposition method for solution of the problem in two level calculation structure is developed on the basis of an augmented functional of Lagrange. A Matlab programme for calculation is written and applied for the fed-batch process for production of yeast
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