扩张型心肌病

P. Masci, V. Maestrini, Deborah H Kwon
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引用次数: 0

摘要

扩张型心肌病(DCM)是普通人群心衰的常见原因。在过去的十年中,由于医学治疗的进步和设备治疗的引入,DCM患者的预后有了显著改善。尽管取得了这些进展,但10年生存率仍<60%,死亡前往往伴有多次心力衰竭加重,这反映了个体风险分层的困难。临床病程差异很大,从进行性心力衰竭或猝死到左心室功能恢复良好,预后良好。心血管磁共振(CMR)在DCM患者的检查中逐渐被接受,可以精确和无创地量化左心室和右心室的体积、质量和功能,以及心肌的组织特征。CMR在DCM患者中发挥着至关重要的临床作用,有助于识别潜在的病因,评估新的CMR预后标志物,改善风险分层。最近的证据也表明,CMR在选择可能从器械治疗中获益的候选人方面发挥了作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dilated cardiomyopathy
Dilated cardiomyopathy (DCM) is a common cause of heart failure in the general population. In the past decade, the prognosis of DCM patients has improved significantly, thanks to advances in medical therapy and the introduction of device(s) treatment. Despite these advances, the 10-year survival remains <60%, with deaths often preceded by numerous heart failure exacerbations, reflecting the difficulty associated with individual risk stratification. The clinical course varies widely, ranging from progressive heart failure or sudden death to excellent recovery of left ventricular function and good prognosis. Cardiovascular magnetic resonance (CMR) has progressively gained acceptance in the workup of patients with DCM, allowing a precise and non-invasive quantification of left and right ventricular volumes, mass, and function, along with tissue characterization of the myocardium. CMR plays a crucial clinical role in DCM patients by helping to identify the potential aetiology and to assess for novel CMR prognostic markers improving risk stratification. Recent evidence also suggests that CMR has a role in the selection of candidates who likely benefit from device(s) therapy.
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