[标题页i]

G. Chew, D. Huang, C. Huo, T. Blick, P. Hill, J. Cawson, H. Frazer, M., D. Southey, J. Hopper, M. Henderson, I. Haviv, E. W. Thompson
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引用次数: 0

摘要

简介:乳房x线摄影密度(MD)是乳腺癌的一个强大的遗传危险因素,并可能随着胎次的增加而降低。然而,md相关乳腺癌的生物分子基础尚不清楚,全身激素对md相关风险的影响也知之甚少。本研究评估了小鼠围产期状态对人类MD异种移植模型中维持的高MD和低MD组织的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Title page i]
Introduction: Mammographic density (MD) is a strong heritable risk factor for breast cancer, and may decrease with increasing parity. However, the biomolecular basis for MD-associated breast cancer remains unclear, and systemic hormonal effects on MDassociated risk is poorly understood. This study assessed the effect of murine peripartum states on high and low MD tissue maintained in a xenograft model of human MD.
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