腹腔镜与常规手术治疗肝包虫病的比较研究

A. Malik, Idrees Ayoub, M. Wani, S. Bari
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引用次数: 1

摘要

背景:腹腔镜下肝包虫病的治疗与腹腔镜手术的发展同步发生了革命性的变化。由于在世界范围内缺乏经验,关于肝包虫病的腹腔镜治疗的争议尚未得到解决。目的:本研究的目的是比较腹腔镜入路与开放手术治疗肝包虫病的手术效果。方法:回顾性和前瞻性研究于2008年1月至2016年1月在印度斯利那加的克什米尔医学科学研究所斯利那加外科外科进行。本研究纳入所有诊断为肝包虫病的成年患者,研究患者总数为80例。所有患者术前和术后均给予阿苯达唑治疗。患者交替采用腹腔镜入路或开放入路。对于回顾性纳入的数据,患者根据他们所经历的手术类型被分为两组。随访时间为1 - 6年,平均随访时间为24个月。所有的数据都以详细的形式输入并分析。结果:开腹组平均年龄40.27岁,腹腔镜组平均年龄38.80岁。大多数患者(55%)表现为腹部疼痛。平均手术时间:开放组60.43 min,腹腔镜组89.80 min。腹腔镜组2例(5%)转为开腹。腹腔镜组平均住院时间3.40天,非腹腔镜组平均住院时间8.73天。Meantimetoreturntoworkwas8.10daysinlaparoscopicgroupand20.70daysinopengroup。腹腔镜组无手术部位感染,而开放组4例(10%)有手术部位感染。在laparoscopicgroup biliaryleakwasseenin3(7.5%)患者,whileinopengroupitwasseenin2(5%)的病人。2例(5%)开腹手术患者出现复发,而腹腔镜手术患者均未出现复发。结论:基于我们目前令人鼓舞的研究结果,我们得出结论,腹腔镜包虫病手术对于符合标准的选定患者是安全可行的,主要是由于术后发病率、死亡率和复发率较低。腹腔镜组无复发,而开放组复发率为5%。在我们的研究中,较低的复发率归因于肝囊肿患者术前和术后使用阿必达-唑。各种研究(17)表明,术前和术后阿苯达唑治疗的患者零复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Laparoscopic Versus Conventional Surgery for Hepatic Hydatid Disease: A Comparative Study
Background: laparoscopic treatment of hepatic hydatid disease has undergone revolution in parallel to progress in laparoscopic surgery. Controversiesabouttherolelaparoscopyinthemanagementof liverhydatidcysthavenotbeenresolvedbecauseof scarce experience worldwide. Objectives: The aim of our study was to compare surgical outcome of laparoscopic approach with open surgery for the management of hepatic hydatid disease. Methods: It was a retrospective and prospective study conducted in the department of surgery SKIMS Srinagar over a period of eight years from January 2008 to January 2016 in Sheri Kashmir institute of medical sciences Srinagar India, Srinagar. The study included all the adult patients admitted with a diagnosis of hepatic hydatid disease and the total number of patients studied was 80. All patients were pre-operatively and post- operatively treated with Albendazole. The patients were alternately taken either for laparoscopic approach or for open approach. For data that was included retrospectively patients were enrolled in either groups based upon the type of surgery they had undergone. Patients were followed for any recurrence for a period ranging from one year to six years with an average follow up period of 24 months. All the data was entered in detailed proforma and analysed. Results: Mean age of presentation was 40.27 years in open group and 38.80 years for laparoscopic group. Majority of patients (55%) presented with pain abdomen. Mean operative time was 60.43 minutes in open group and 89.80 min. for laparoscopic group. Two patients (5%) from the laparoscopic group had to be converted to open. In laparoscopic group mean hospital stay was 3.40 days whileinopengroupitwas8.73days. Meantimetoreturntoworkwas8.10daysinlaparoscopicgroupand20.70daysinopengroup. In laparoscopic group none of the patients had surgical site infection while as in open group 4 (10%) had surgical site infection. In laparoscopicgroup,biliaryleakwasseenin3(7.5%)patients,whileinopengroupitwasseenin2(5%)patients. Recurrencewasseen in2(5%)patientswhounderwentopensurgery,whileasrecurrencewasnotseeninanyof thepatientswhounderwentlaparoscopic surgery. Conclusions: Based on our encouraging results from our current study, we conclude that laparoscopic hydatid surgery is safe and feasible for selected patients in which criteria is met, motivated primarily by lower post-operative morbidity, mortality and recurrence. there was no recurrence in laparoscopic group while as in open group 5% had recurrence. Lower recurrence in our study was attributed to use of Albenda-zolepreandpostoperativelyinpatientsof hepatichydatid cysts. Variousstudies(17)haveshownzerorecurrencerates in patients treated with Albendazole pre and post operatively.
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