Prevalence and reasons associated with antibiotics misuse and self-medication among adults in Nigeria: A systematic review and meta-analysis [Protocol]

There is consistent increase in prevalence of antibiotics misuse and self-medication in Nigeria. The exact quality of information available in the public domain is unknown. There is no previous systematic review and meta-analysis that address antibiotics misuse and self-medication in Nigeria. Being the most populous country in Africa, understanding the drivers of antibiotics misuse and self-medication will impact in not only Nigeria, but Africa as a whole. The aim of this systematic review and meta-analysis is therefore to determine the prevalence and factors associated with antibiotics misuse and self-medication among adults in Nigeria. Attempt will be made to find and include published papers on prevalence and reasons associated with antibiotics misuse and self-medication among adults in Nigeria from 2011-2021. Systematic search for the literature will be conducted according to the Preferred Reporting Item for Systematic Reviews and Meta-Analysis (PRISMA) guidelines to identified published studies based on our predetermined inclusion and exclusion criteria in PubMed, EMBASE, PsychINFO, CINAHL and Web of Sciences. Two independent reviewers will assess all identified studies and another set of reviewers will extract data for analysis and evidence synthesis.