ADM (Dermacell)治疗手部肥厚性瘢痕(HSs)后挛缩性瘢痕

Spyridon Maragkos, Giampietro Bertasi, Mariana Peroni
{"title":"ADM (Dermacell)治疗手部肥厚性瘢痕(HSs)后挛缩性瘢痕","authors":"Spyridon Maragkos, Giampietro Bertasi, Mariana Peroni","doi":"10.53294/ijfstr.2022.3.2.0052","DOIUrl":null,"url":null,"abstract":"Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.","PeriodicalId":199114,"journal":{"name":"International Journal of Frontiers in Science and Technology Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Treatment of retractile scar after a hypetrophic scar (HSs) in the hand with ADM (Dermacell)\",\"authors\":\"Spyridon Maragkos, Giampietro Bertasi, Mariana Peroni\",\"doi\":\"10.53294/ijfstr.2022.3.2.0052\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.\",\"PeriodicalId\":199114,\"journal\":{\"name\":\"International Journal of Frontiers in Science and Technology Research\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Frontiers in Science and Technology Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53294/ijfstr.2022.3.2.0052\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Frontiers in Science and Technology Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53294/ijfstr.2022.3.2.0052","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

在皮肤损伤或伤口后,增生性疤痕可以出现在皮肤的任何地方。原因尚不完全清楚,其结果是多余胶原蛋白的异常产生和弹性蛋白的减少,从而导致这些不受欢迎的厚,凸起的僵硬疤痕。有时会进行手术切除疤痕或重新定位疤痕上的张力线。通常,当其他治疗方案失败时,会考虑手术。真皮细胞是人类脱细胞基质(hADM),用于软组织修复的补充支持和覆盖。它起到了ECM的作用。细胞外基质(ECM)分子在真皮中的表达和增殖,由一系列生长因子和细胞因子介导,是伤口修复的基本要素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Treatment of retractile scar after a hypetrophic scar (HSs) in the hand with ADM (Dermacell)
Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信