颞叶肿瘤脱位过程的断层和形态学特征

J. Gvazava, G. Gvazava
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引用次数: 0

摘要

背景:脱位是颞叶肿瘤的严重并发症。颞叶肿瘤的特点是高脱位率。颞叶中基底部在地形上最靠近松孔,确保脱位综合征的形成,局部症状优于常见的大脑症状。目的:研究颞叶肿瘤脱位过程的结构相关性和形态学特征,以确定最佳的手术治疗方法。方法:对85例颞叶肿瘤切面材料脱位(男53例,女32例)进行分析。所有的肿瘤材料都是基于手术和断层材料的显微镜、宏观和电镜检查,并通过大脑的许多额状和矢状切口进行验证。结果:肿瘤中基底定位未发现任何良性肿瘤。在6例(7%)的病例中,形态代偿非常高,我们无法发现肿瘤与脱位之间的任何联系。部分病例海马回和扣带回未被挤压。在颞叶肿瘤引起的脱位过程中,大孔扁桃体疝发生较晚,终末时在小脑半球可能未发生粗陋的形态学改变。可考虑脑继发性缺血的因素。大孔的突出造成了茎部重要功能的破坏,这是快速死亡的原因。结论:脱位多发生在高级别恶性胶质瘤组,主要发生在颞叶中基底部。除肿瘤病理作用外,脱位的实现是脑继发性缺血的因素,是肿瘤对大脑中动脉主干和分支的压迫所致。从我们的观点来看,快死的原因是比沙洞的突出。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sectional and Morphological features of dislocation process during the temporal lobe tumors
Background: Dislocation is the terrible complication of the temporal lobe tumors. The tumors of the temporal lobe are characterized by high rate of dislocation. Topographilly nearest of medio-basal part of temporal lobe to Pachion hole ensuring the formation of dislocation syndrome and preponderate of local symptoms over common cerebral symptoms. Aim: The aim of our research is to study a structural correlation and morphological features of dislocation process during temporal lobe tumors for definition optimal surgical treatment. Methods: We studied 85 dislocation cases of sectional material during temporal lobe tumors (53 males and 32 famales). All material of tumors were based on the microscope, macroscope and electro-microscope examination of operative and sectional material and were verified by many frontal and sagittal incisions of the brain. Results: In medio-basal localization of tumors we didn’t meet any benign tumors. In 6 (7%) of cases morphological compensation was so high, that we couldn’t find any connection between tumor and dislocation. Some cases gyrus hippocampus and cingula were not pinched. During the dislocation process caused by temporal lobe tumors herniating of tonsila in the foramen Magna happens late, at the end, when in the cerebellum hemisphere may not happened rude morpho-logical changes. The factor of secondary ischemia of the brain may be considered. The herniation in the foramen Magna caused the ruin of vital functions in the stem, which is the reason of quick death. Conclusions: Dislocation mostly occurred in the group of malign glioms of high grade, mainly lo-calized in the medio-basal part of the temporal lobe. The realization of dislocation besides tumors pathobiological action is the factor of brain secondary ischemia, which is caused by the pressure of tumors on the main trunk and branches of the middle cerebral artery. From our point of view the reason of quick death is the herniation in the hole of Bisha.
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